RAVI SALGIA

ONCOLOGY Arthur & Rosalie Kaplan Chair in Medical Oncology; Chairman, Department of Medical Oncology City of Hope

Dr. Ravi Salgia is an internationally recognized physician-scientist. He has made seminal contributions to lung cancer which led to new therapeutics, especially those targeting receptor tyrosine kinases that play an important role in the disease pathology. He discovered the MET exon 14 deletion in non-small cell lung cancer against which tepotinib was developed and is approved for treating patients. More recently, Dr. Salgia has focused on the nongenetic mechanisms underlying drug resistance in lung cancer. He was the first to clone the cDNA encoding human paxillin and demonstrated its role in metastasis and in causing resistance to chemotherapy.